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Simultaneous Mutation of Methylated Lysine Residues in Histone H3 Causes Enhanced Gene Silencing, Cell Cycle Defects, and Cell Lethality in Saccharomyces cerevisiae

The methylation of specific lysine residues in histone H3 is integral to transcription regulation; however, little is known about how combinations of methylated lysine residues act in concert to regulate genome-wide transcription. We have systematically mutated methylated histone lysine residues in...

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Bibliografiske detaljer
Main Authors: Jin, Yi, Rodriguez, Amy M., Stanton, Julie D., Kitazono, Ana A., Wyrick, John J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099221/
https://ncbi.nlm.nih.gov/pubmed/17664279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00745-07
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