MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover

Mitotic centromere-associated kinesin (MCAK)/Kif2C is the most potent microtubule (MT)-destabilizing enzyme identified thus far. However, MCAK's function at the centromere has remained mechanistically elusive because of interference from cytoplasmic MCAK's global regulation of MT dynamics....

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Bibliographic Details
Main Authors: Wordeman, Linda, Wagenbach, Michael, von Dassow, George
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099197/
https://ncbi.nlm.nih.gov/pubmed/18039936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707120
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