Vinculin controls focal adhesion formation by direct interactions with talin and actin

Focal adhesions (FAs) regulate cell migration. Vinculin, with its many potential binding partners, can interconnect signals in FAs. Despite the well-characterized structure of vinculin, the molecular mechanisms underlying its action have remained unclear. Here, using vinculin mutants, we separate th...

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Autores principales: Humphries, Jonathan D., Wang, Pengbo, Streuli, Charles, Geiger, Benny, Humphries, Martin J., Ballestrem, Christoph
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099183/
https://ncbi.nlm.nih.gov/pubmed/18056416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703036
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