High osmolarity is a signal for enhanced algD transcription in mucoid and nonmucoid Pseudomonas aeruginosa strains.

Chronic lung infection with mucoid, alginate-producing strains of Pseudomonas aeruginosa is a major cause of mortality in cystic fibrosis (CF) patients. Transcriptional activation of the P. aeruginosa algD gene, which encodes GDPmannose dehydrogenase, is essential for alginate synthesis. Activation...

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Bibliografiske detaljer

Udgivet i:	J Bacteriol
Principais autores:	Berry, A, DeVault, J D, Chakrabarty, A M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2496102/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.5.2312-2317.1989
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