High osmolarity is a signal for enhanced algD transcription in mucoid and nonmucoid Pseudomonas aeruginosa strains.

Chronic lung infection with mucoid, alginate-producing strains of Pseudomonas aeruginosa is a major cause of mortality in cystic fibrosis (CF) patients. Transcriptional activation of the P. aeruginosa algD gene, which encodes GDPmannose dehydrogenase, is essential for alginate synthesis. Activation...

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Huvudupphovsmän: Berry, A, DeVault, J D, Chakrabarty, A M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1989
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC209903/
https://ncbi.nlm.nih.gov/pubmed/2496102
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