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Identification of toxS, a regulatory gene whose product enhances toxR-mediated activation of the cholera toxin promoter.

We describe the cloning of the toxS gene from Vibrio cholerae E1 Tor strain E7946. This gene lies downstream from the toxR gene, which encodes the transcriptional activator for the cholera toxin (ctx) operon in V. cholerae. We show that ToxS acts in conjunction with ToxR to activate expression of th...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Miller, V L, DiRita, V J, Mekalanos, J J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2646275/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.3.1288-1293.1989
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