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Tissue factor transcription driven by Egr-1 is a critical mechanism of murine pulmonary fibrin deposition in hypoxia

Local hypoxemia and stasis trigger thrombosis. We have demonstrated previously that in a murine model of normobaric hypoxia pulmonary fibrin deposition is a result of expression of tissue factor, especially in oxygen-deprived mononuclear phagocytes (MPs). We now show that transcription factor early-...

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Detalhes bibliográficos
Main Authors: Yan, Shi-Fang, Zou, Yu Shan, Gao, Yun, Zhai, Chao, Mackman, Nigel, Lee, Stephen L., Milbrandt, Jeffrey, Pinsky, David, Kisiel, Walter, Stern, David
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20970/
https://ncbi.nlm.nih.gov/pubmed/9653181
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