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Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition.

Oxygen deprivation, as occurs during tissue ischemia, tips the natural anticoagulant/procoagulant balance of the endovascular wall to favor activation of coagulation. To investigate the effects of low ambient oxygen tension on the fibrinolytic system, mice were placed in a hypoxic environment with p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pinsky, D J, Liao, H, Lawson, C A, Yan, S F, Chen, J, Carmeliet, P, Loskutoff, D J, Stern, D M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC508957/
https://ncbi.nlm.nih.gov/pubmed/9727060
Etiketak: Etiketa erantsi
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