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Prior Activation of Kappa Opioid Receptors by U50,488 Mimics Repeated Forced Swim Stress to Potentiate Cocaine Place Preference Conditioning

Repeated forced-swim stress (FSS) produced analgesia, immobility and potentiation of cocaine-conditioned place preference (CPP) in wild-type C57Bl/6 mice, but not in littermates lacking the kappa opioid receptor (KOR) gene. These results were surprising because kappa agonists are known to produce co...

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Detalhes bibliográficos
Main Authors: McLaughlin, Jay P, Land, Benjamin B, Li, Shuang, Pintar, John E, Chavkin, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096772/
https://ncbi.nlm.nih.gov/pubmed/16123754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1300860
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