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The C. elegans pumilio homolog, puf-9, is required for the 3’UTR mediated repression of the let-7 microRNA target gene, hbl-1.
The Puf family of RNA-binding proteins directs cell fates by regulating gene expression at the level of translation and RNA stability. Here, we report that the C. elegans pumilio homolog, puf-9, controls the differentiation of epidermal stem cells at the larval-to-adult transition. Genetic analysis...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2096746/ https://ncbi.nlm.nih.gov/pubmed/17412319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.02.040 |
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