Characterization of human and rodent native and recombinant adenosine A(2B) receptors by radioligand binding studies

Adenosine A(2B) receptors of native human and rodent cell lines were investigated using [(3)H]PSB-298 [(8-{4-[2-(2-hydroxyethylamino)-2-oxoethoxy]phenyl}-1-propylxanthine] in radioligand binding studies. [(3)H]PSB-298 showed saturable and reversible binding. It exhibited a K(D) value of 60 ± 1 nM an...

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Asıl Yazarlar: Bertarelli, Daniela C. G., Diekmann, Martina, Hayallah, Alaa M., Rüsing, Dorothee, Iqbal, Jamshed, Preiss, Birgit, Verspohl, Eugen J., Müller, Christa E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Netherlands 2006
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096648/
https://ncbi.nlm.nih.gov/pubmed/18404493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-006-9012-4
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