Transactivation of Vascular Endothelial Growth Factor Receptor-2 by Interleukin-8 (IL-8/CXCL8) Is Required for IL-8/CXCL8-induced Endothelial Permeability

Interleukin-8 (IL-8/CXCL8) is a chemokine that increases endothelial permeability during early stages of angiogenesis. However, the mechanisms involved in IL-8/CXCL8-induced permeability are poorly understood. Here, we show that permeability induced by this chemokine requires the activation of vascu...

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Autori principali: Petreaca, Melissa L., Yao, Min, Liu, Yan, DeFea, Kathryn, Martins-Green, Manuela
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096609/
https://ncbi.nlm.nih.gov/pubmed/17928406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-01-0004
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