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Extracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targets

In this review, we focus on two attributes of P2X receptor channel function, one essential and one novel. First, we propose that P2X receptors are extracellular sensors as well as receptors and ion channels. In particular, the large extracellular domain (that comprises 70% of the molecular mass of t...

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Detalhes bibliográficos
Main Authors: Schwiebert, Erik M., Liang, Lihua, Cheng, Nai-Lin, Williams, Clintoria Richards, Olteanu, Dragos, Welty, Elisabeth A., Zsembery, Akos
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096558/
https://ncbi.nlm.nih.gov/pubmed/18404515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-005-0777-7
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