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Extracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targets

In this review, we focus on two attributes of P2X receptor channel function, one essential and one novel. First, we propose that P2X receptors are extracellular sensors as well as receptors and ion channels. In particular, the large extracellular domain (that comprises 70% of the molecular mass of t...

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Autors principals: Schwiebert, Erik M., Liang, Lihua, Cheng, Nai-Lin, Williams, Clintoria Richards, Olteanu, Dragos, Welty, Elisabeth A., Zsembery, Akos
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096558/
https://ncbi.nlm.nih.gov/pubmed/18404515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-005-0777-7
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