P2X(7) nucleotide receptors mediate caspase-8/9/3-dependent apoptosis in rat primary cortical neurons

Apoptosis is a major cause of cell death in the nervous system. It plays a role in embryonic and early postnatal brain development and contributes to the pathology of neurodegenerative diseases. Here, we report that activation of the P2X(7) nucleotide receptor (P2X(7)R) in rat primary cortical neuro...

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Detalhes bibliográficos
Main Authors: Kong, Qiongman, Wang, Min, Liao, Zhongji, Camden, Jean M., Yu, Sue, Simonyi, Agnes, Sun, Grace Y., Gonzalez, Fernando A., Erb, Laurie, Seye, Cheikh I., Weisman, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096553/
https://ncbi.nlm.nih.gov/pubmed/18404518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-005-7145-5
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