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Impairment of mitochondrial acetoacetyl CoA thiolase activity in the colonic mucosa of patients with ulcerative colitis

BACKGROUND AND AIMS: Butyrate oxidation by colonocytes is impaired in ulcerative colitis. This study examined the activity of enzymes involved in butyrate oxidation in ulcerative colitis. METHODS: Activities of mitochondrial acetoacetyl coenzyme A (CoA) thiolase, crotonase and β‐hydroxy butyryl CoA...

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Hlavní autoři: Santhanam, Srikanth, Venkatraman, Aparna, Ramakrishna, Balakrishnan S
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095666/
https://ncbi.nlm.nih.gov/pubmed/17483192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.108449
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