Synergistic effects of RXRα and PPARγ ligands to inhibit growth in human colon cancer cells—phosphorylated RXRα is a critical target for colon cancer management

BACKGROUND AND AIMS: The activation of the peroxisome proliferator‐activated receptor γ (PPARγ) that forms heterodimers with retinoid X receptors (RXRs) elicits an antineoplastic effect on colorectal cancer. It was previously reported that the accumulation of the non‐functional phosphorylated form o...

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Detalhes bibliográficos
Main Authors: Yamazaki, Kenji, Shimizu, Masahito, Okuno, Masataka, Matsushima‐Nishiwaki, Rie, Kanemura, Nobuhiro, Araki, Hiroshi, Tsurumi, Hisashi, Kojima, Soichi, Weinstein, I Bernard, Moriwaki, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Colorectal Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095663/
https://ncbi.nlm.nih.gov/pubmed/17604322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2007.129858
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