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Efficient adenoviral infection with IκBα reveals that macrophage tumor necrosis factor α production in rheumatoid arthritis is NF-κB dependent

Tumor necrosis factor (TNF) α has been shown to be a major therapeutic target in rheumatoid arthritis with the success of anti-TNFα antibody clinical trials. Although signaling pathways leading to TNFα expression have been studied in some detail, there is evidence for considerable differences betwee...

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Detalhes bibliográficos
Main Authors: Foxwell, Brian, Browne, Kylie, Bondeson, Jan, Clarke, Chris, de Martin, Rainer, Brennan, Fionula, Feldmann, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20955/
https://ncbi.nlm.nih.gov/pubmed/9653166
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