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Efficient adenoviral infection with IκBα reveals that macrophage tumor necrosis factor α production in rheumatoid arthritis is NF-κB dependent

Tumor necrosis factor (TNF) α has been shown to be a major therapeutic target in rheumatoid arthritis with the success of anti-TNFα antibody clinical trials. Although signaling pathways leading to TNFα expression have been studied in some detail, there is evidence for considerable differences betwee...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Foxwell, Brian, Browne, Kylie, Bondeson, Jan, Clarke, Chris, de Martin, Rainer, Brennan, Fionula, Feldmann, Marc
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653166/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.8211
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