Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers

BACKGROUND: Recent reports indicate that prostate cancers (CaP) frequently over‐express the potential oncogenes, ERG or ETV1. Many cases have chromosomal rearrangements leading to the fusion of the 5′ end of the androgen‐regulated serine protease TMPRSS2 (21q22.2) to the 3′ end of either ERG (21q22....

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Detalhes bibliográficos
Main Authors: Rajput, Ashish B, Miller, Melinda A, De Luca, Alessandro, Boyd, Niki, Leung, Sam, Hurtado‐Coll, Antonio, Fazli, Ladan, Jones, Edward C, Palmer, Jodie B, Gleave, Martin E, Cox, Michael E, Huntsman, David G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095486/
https://ncbi.nlm.nih.gov/pubmed/17259299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2006.043810
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