Role of AMP-activated protein kinase in mechanism of metformin action

Metformin is a widely used drug for treatment of type 2 diabetes with no defined cellular mechanism of action. Its glucose-lowering effect results from decreased hepatic glucose production and increased glucose utilization. Metformin’s beneficial effects on circulating lipids have been linked to red...

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Main Authors: Zhou, Gaochao, Myers, Robert, Li, Ying, Chen, Yuli, Shen, Xiaolan, Fenyk-Melody, Judy, Wu, Margaret, Ventre, John, Doebber, Thomas, Fujii, Nobuharu, Musi, Nicolas, Hirshman, Michael F., Goodyear, Laurie J., Moller, David E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2001
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC209533/
https://ncbi.nlm.nih.gov/pubmed/11602624
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