Wordt geladen...
Constitutive β cell expression of IL-12 does not perturb self-tolerance but intensifies established autoimmune diabetes
To analyze the function of the Th1-promoting cytokine IL-12 in vivo, we generated transgenic (tg) mice (RIP-IL12 mice) whose pancreatic β cells constitutively express bioactive IL-12 or one of its components, p35 or p40. In contrast to non-tg littermates or single-tg RIP-p35 and RIP-p40 mice, RIP-IL...
Bewaard in:
| Hoofdauteurs: | , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
2001
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC209472/ https://ncbi.nlm.nih.gov/pubmed/11748258 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|