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sud1(+) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast

In the fission yeast Schizosaccharomyces pombe, S phase is limited to a single round per cell cycle through cyclin-dependent kinase phosphorylation of critical replication factors, including the Cdc18 replication initiator protein. Because defects in Cdc18 phosphorylation lead to a hyperstable and h...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Jallepalli, Prasad V., Tien, Deborah, Kelly, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653157/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.8159
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