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STAT4 and STAT6 regulate systemic inflammation and protect against lethal endotoxemia

Members of the signal transducer and activator of transcription (STAT) family are transcription factors that mediate many of the effects of pro- and anti-inflammatory cytokines. The progressive systemic inflammatory response induced by endotoxin is mediated by overzealous cytokine production. Here w...

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Udgivet i:J Clin Invest
Principais autores: Lentsch, Alex B., Kato, Atsushi, Davis, Brian, Wang, Warner, Chao, Celia, Edwards, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209422/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11714739/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13763
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