Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity

A series of events initiated by glutamate-receptor interaction perturbs cellular homeostasis resulting in elevation of intracellular free calcium and cell death. Cells subject to such environmental change express stress proteins, which contribute importantly to maintenance of metabolic homeostasis a...

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Main Authors: Kitao, Yasuko, Ozawa, Kentaro, Miyazaki, Mayuki, Tamatani, Michio, Kobayashi, Tomohiro, Yanagi, Hideki, Okabe, Masaru, Ikawa, Masahito, Yamashima, Tetsumori, Stern, David M., Hori, Osamu, Ogawa, Satoshi
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC209417/
https://ncbi.nlm.nih.gov/pubmed/11714735
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