Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis

BACKGROUND/AIMS: Studies in animal models and humans suggest a link between endotoxemia and non-alcoholic steatohepatitis. Since Kupffer cells are responsible for clearing endotoxin and are activated via endotoxin interaction with Toll-like receptor 4 (TLR-4), we examined the relationship between he...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rivera, Chantal A., Adegboyega, Patrick, van Rooijen, Nico, Tagalicud, Arlene, Allman, Monique, Wallace, Matthew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094119/
https://ncbi.nlm.nih.gov/pubmed/17644211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2007.04.019
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