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Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis

BACKGROUND: Previously we reported that mice deficient in toll-like receptor 4 (TLR-4) signalling were protected from diet-induced non-alcoholic steatohepatitis (NASH). Another member of the toll-like receptor family, TLR-2, has been shown to play a role in lipid trafficking via uptake of diacylated...

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Detalhes bibliográficos
Main Authors: Rivera, Chantal A, Gaskin, LaTausha, Allman, Monique, Pang, Jia, Brady, Kristen, Adegboyega, Patrick, Pruitt, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891617/
https://ncbi.nlm.nih.gov/pubmed/20509914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-10-52
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