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Tissue Expression and Genomic Sequences of Rat N-acetyltransferases rNat1, rNat2, rNat3, and Functional Characterization of a Novel rNat3*2 Genetic Variant

Human arylamine N-acetyltransferases NAT1 and NAT2 are highly polymorphic genes that modify individual susceptibility to cancers caused by exposure to arylamine pro-carcinogens. Strong similarities exist between rat Nats and human NATs, and rat Nat2 polymorphisms result in slow acetylator phenotype....

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書誌詳細
主要な著者: Walraven, Jason M., Barker, David F., Doll, Mark A., Hein, David W.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094101/
https://ncbi.nlm.nih.gov/pubmed/17567587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfm159
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