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Back to basics: the untreated rabbit reticulocyte lysate as a competitive system to recapitulate cap/poly(A) synergy and the selective advantage of IRES-driven translation

Translation of most eukaryotic mRNAs involves the synergistic action between the 5′ cap structure and the 3′ poly(A) tail at the initiation step. The poly(A) tail has also been shown to stimulate translation of picornavirus internal ribosome entry sites (IRES)-directed translation. These effects hav...

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Detalhes bibliográficos
Main Authors: Rifo, Ricardo Soto, Ricci, Emiliano P., Décimo, Didier, Moncorgé, Olivier, Ohlmann, Théophile
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094066/
https://ncbi.nlm.nih.gov/pubmed/17881372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm682
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