Stabilization of SMAR1 mRNA by PGA2 involves a stem–loop structure in the 5′ UTR

Prostaglandins are anticancer agents known to inhibit tumor cell proliferation both in vitro and in vivo by affecting the mRNA stability. Here we report that a MAR-binding protein SMAR1 is a target of Prostaglandin A2 (PGA2) induced growth arrest. We identify a regulatory mechanism leading to stabil...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Pavithra, Lakshminarasimhan, Rampalli, Shravanti, Sinha, Surajit, Sreenath, Kadreppa, Pestell, Richard G., Chattopadhyay, Samit
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2007
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094063/
https://ncbi.nlm.nih.gov/pubmed/17726044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm649
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker