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The crystal structure of human E-cadherin domains 1 and 2, and comparison with other cadherins in the context of adhesion mechanism

Cell adhesion mediated by type I cadherins involves homophilic “trans” interactions that are thought to be brought about by a strand exchange mechanism involving the N-terminal extracellular domain. Here, we present the high-resolution crystal structure of the N-terminal two domains of human E-cadhe...

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Detalhes bibliográficos
Main Authors: Parisini, Emilio, Higgins, Jonathan M.G., Liu, Jin-huan, Brenner, Michael B., Wang., Jia-huai
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094043/
https://ncbi.nlm.nih.gov/pubmed/17850815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.08.011
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