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Mutation Analysis of BRAF, MEK1 and MEK2 in 15 Ovarian Cancer Cell Lines: Implications for Therapy

BACKGROUND: Among gynecologic cancers, ovarian cancer is the second most common and has the highest death rate. Cancer is a genetic disorder and arises due to the accumulation of somatic mutations in critical genes. An understanding of the genetic basis of ovarian cancer has implications both for ea...

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Bibliografiska uppgifter
Huvudupphovsmän: Estep, Anne L., Palmer, Chana, McCormick, Frank, Rauen, Katherine A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2093994/
https://ncbi.nlm.nih.gov/pubmed/18060073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001279
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