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TNF-α mediates SDF-1α–induced NF-κB activation and cytotoxic effects in primary astrocytes

Stromal-derived cell factor-1α (SDF-1α; CXCL12) and its receptor, CXCR4, are constitutively expressed on neuroepithelial cells and are believed to be involved in both development and pathological processes, such as AIDS-associated neurologic disorders. Here, we demonstrate that SDF-1α activates NF-κ...

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Autors principals: Han, Yulong, He, Tao, Huang, DeRen, Pardo, Carlos A., Ransohoff, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC209361/
https://ncbi.nlm.nih.gov/pubmed/11489936
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