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Reversal of established autoimmune diabetes by restoration of endogenous β cell function

In NOD (nonobese diabetic) mice, a model of autoimmune diabetes, various immunomodulatory interventions prevent progression to diabetes. However, after hyperglycemia is established, such interventions rarely alter the course of disease or allow sustained engraftment of islet transplants. A proteasom...

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Detalhes bibliográficos
Main Authors: Ryu, Shinichiro, Kodama, Shohta, Ryu, Kazuko, Schoenfeld, David A., Faustman, Denise L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209340/
https://ncbi.nlm.nih.gov/pubmed/11435458
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