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Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

ADP is an important platelet agonist causing shape change and aggregation required for physiological hemostasis. We recently demonstrated the existence of two distinct G protein-coupled ADP receptors on platelets, one coupled to phospholipase C, P2Y1, and the other to inhibition of adenylyl cyclase,...

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Autors principals: Jin, Jianguo, Kunapuli, Satya P.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20930/
https://ncbi.nlm.nih.gov/pubmed/9653141
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