Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation
ADP is an important platelet agonist causing shape change and aggregation required for physiological hemostasis. We recently demonstrated the existence of two distinct G protein-coupled ADP receptors on platelets, one coupled to phospholipase C, P2Y1, and the other to inhibition of adenylyl cyclase,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20930/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653141/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.8070 |
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