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Osteoprotegerin inhibits prostate cancer–induced osteoclastogenesis and prevents prostate tumor growth in the bone

Prostate cancer (CaP) forms osteoblastic skeletal metastases with an underlying osteoclastic component. However, the importance of osteoclastogenesis in the development of CaP skeletal lesions is unknown. In the present study, we demonstrate that CaP cells directly induce osteoclastogenesis from ost...

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Detalhes bibliográficos
Main Authors: Zhang, Jian, Dai, Jinlu, Qi, Yinghua, Lin, Din-Lii, Smith, Peter, Strayhorn, Chris, Mizokami, Atsushi, Fu, Zheng, Westman, John, Keller, Evan T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209296/
https://ncbi.nlm.nih.gov/pubmed/11375413
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