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Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways

Hepatic steatosis is common in patients having severe hyperhomocysteinemia due to deficiency for cystathionine β-synthase. However, the mechanism by which homocysteine promotes the development and progression of hepatic steatosis is unknown. We report here that homocysteine-induced endoplasmic retic...

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Bibliografische gegevens
Hoofdauteurs: Werstuck, Geoff H., Lentz, Steven R., Dayal, Sanjana, Hossain, Gazi S., Sood, Sudesh K., Shi, Yuan Y., Zhou, Ji, Maeda, Nobuyo, Krisans, Skaidrite K., Malinow, M. Rene, Austin, Richard C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC209295/
https://ncbi.nlm.nih.gov/pubmed/11375416
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