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Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway

We have previously shown that the degradation of c-myc and N-myc in vitro is mediated by the ubiquitin system. However, the role of the system in targeting the myc proteins in vivo and the identity of the conjugating enzymes and possible ancillary proteins involved has remained obscure. Here we repo...

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Hlavní autoři: Gross-Mesilaty, Shlomit, Reinstein, Eyal, Bercovich, Beatrice, Tobias, Karin E., Schwartz, Alan L., Kahana, Chaim, Ciechanover, Aaron
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC20928/
https://ncbi.nlm.nih.gov/pubmed/9653139
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