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Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway

We have previously shown that the degradation of c-myc and N-myc in vitro is mediated by the ubiquitin system. However, the role of the system in targeting the myc proteins in vivo and the identity of the conjugating enzymes and possible ancillary proteins involved has remained obscure. Here we repo...

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Main Authors: Gross-Mesilaty, Shlomit, Reinstein, Eyal, Bercovich, Beatrice, Tobias, Karin E., Schwartz, Alan L., Kahana, Chaim, Ciechanover, Aaron
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC20928/
https://ncbi.nlm.nih.gov/pubmed/9653139
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