Heparin-binding defective lipoprotein lipase is unstable and causes abnormalities in lipid delivery to tissues

Lipoprotein lipase (LpL) binding to heparan sulfate proteoglycans (HSPGs) is hypothesized to stabilize the enzyme, localize LpL in specific capillary beds, and route lipoprotein lipids to the underlying tissues. To test these hypotheses in vivo, we created mice expressing a human LpL minigene (hLpL(...

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Xehetasun bibliografikoak
Egile Nagusiak: Lutz, E. Peer, Merkel, Martin, Kako, Yuko, Melford, Kristan, Radner, Herbert, Breslow, Jan L., Bensadoun, André, Goldberg, Ira J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2001
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC209279/
https://ncbi.nlm.nih.gov/pubmed/11342582
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