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Heparin-binding defective lipoprotein lipase is unstable and causes abnormalities in lipid delivery to tissues

Lipoprotein lipase (LpL) binding to heparan sulfate proteoglycans (HSPGs) is hypothesized to stabilize the enzyme, localize LpL in specific capillary beds, and route lipoprotein lipids to the underlying tissues. To test these hypotheses in vivo, we created mice expressing a human LpL minigene (hLpL(...

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Bibliografski detalji
Glavni autori: Lutz, E. Peer, Merkel, Martin, Kako, Yuko, Melford, Kristan, Radner, Herbert, Breslow, Jan L., Bensadoun, André, Goldberg, Ira J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2001
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC209279/
https://ncbi.nlm.nih.gov/pubmed/11342582
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