Absence of hisT-mediated tRNA pseudouridylation results in a uracil requirement that interferes with Escherichia coli K-12 cell division.

We show that hisT function is required for normal growth of Escherichia coli K-12, since a lack of hisT-mediated pseudouridine tRNA modification causes a uracil requirement that interferes with cell division. We also show that hisT transcription is positively growth rate regulated in exponentially g...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Tsui, H C, Arps, P J, Connolly, D M, Winkler, M E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1938930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.22.7395-7400.1991
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