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An MHC-linked locus modulates thymic differentiation of CD4(+)CD25(+)Foxp3(+) regulatory T lymphocytes
CD4(+)CD25(+)Foxp3(+) regulatory T lymphocytes are crucial for maintenance of immunological tolerance to self and innocuous non-self, are known to modulate immunity to tumors and infectious agents, and can induce transplantation tolerance. Surprisingly, only a single genetic polymorphism is known to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
[Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2092413/ https://ncbi.nlm.nih.gov/pubmed/16943258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxl084 |
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