High Pro-Inflammatory Cytokine Secretion and Loss of High Avidity Cross-Reactive Cytotoxic T-Cells during the Course of Secondary Dengue Virus Infection

BACKGROUND: Dengue is one of the most important human diseases transmitted by an arthropod vector and the incidence of dengue virus infection has been increasing – over half the world's population now live in areas at risk of infection. Most infections are asymptomatic, but a subset of patients...

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Autors principals: Dong, Tao, Moran, Edward, Vinh Chau, Nguyen, Simmons, Cameron, Luhn, Kerstin, Peng, Yanchun, Wills, Bridget, Phuong Dung, Nguyen, Thi Thu Thao, Le, Hien, Tran Tinh, McMichael, Andrew, Farrar, Jeremy, Rowland-Jones, Sarah
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2092391/
https://ncbi.nlm.nih.gov/pubmed/18060049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001192
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