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Preservation of a critical epitope core region is associated with the high degree of flaviviral cross-reactivity exhibited by a dengue-specific CD4(+) T cell clone

Dengue is a member of the Flaviviridae, a large group of related viruses some of which co-circulate in certain regions (e.g. dengue and Yellow fever in South America). Immune responses cross-reactive between different dengue serotypes are important in the pathogenesis of dengue disease but it is not...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Immunol
Hauptverfasser: Moran, Edward, Simmons, Cameron, Chau, Nguyen Vinh, Luhn, Kerstin, Wills, Bridget, Phuong Dung, Nguyen, Thao, Le Thi Thu, Hien, Tran Tinh, Farrar, Jeremy, Rowland-Jones, Sarah, Dong, Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333208/
https://ncbi.nlm.nih.gov/pubmed/18383038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737699
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