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An N-terminal fragment of the gene 4 helicase/primase of bacteriophage T7 retains primase activity in the absence of helicase activity

Primase and helicase activities of bacteriophage T7 are present in a single polypeptide coded by gene 4. Because the amino terminal region of the gene 4 protein contributes to primase activity, we constructed a truncated gene 4 encoding the N-terminal 271-aa residues. The truncated protein, purified...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Frick, David N., Baradaran, Khandan, Richardson, Charles C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1998
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653122/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.7957
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