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Role of Fission Yeast Primase Catalytic Subunit in the Replication Checkpoint

To investigate the cell cycle checkpoint response to aberrant S phase-initiation, we analyzed mutations of the two DNA primase subunit genes of Schizosaccharomyces pombe, spp1(+) and spp2(+) (S. pombe primase 1 and 2). spp1(+) encodes the catalytic subunit that synthesizes the RNA primer, which is t...

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Autors principals: Griffiths, Dominic J. F., Liu, Vivian F., Nurse, Paul, Wang, Teresa S.-F.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC30572/
https://ncbi.nlm.nih.gov/pubmed/11160827
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