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Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn’s disease

We describe here the immunologic characterization of a new mouse strain, SAMP1/Yit, which spontaneously develops a chronic intestinal inflammation localized to the terminal ileum. The resulting ileitis bears a remarkable resemblance to human Crohn’s disease. This strain of mice develops discontinuou...

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Bibliografski detalji
Glavni autori: Kosiewicz, Michele M., Nast, Cynthia C., Krishnan, Anasuya, Rivera-Nieves, Jesus, Moskaluk, Christopher A., Matsumoto, Satoshi, Kozaiwa, Kosuke, Cominelli, Fabio
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC208944/
https://ncbi.nlm.nih.gov/pubmed/11254669
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