Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model

Although hyperhomocysteinemia (HHcy) is a well-known risk factor for the development of cardiovascular disease, the underlying molecular mechanisms are not fully elucidated. Here we show that induction of HHcy in apoE-null mice by a diet enriched in methionine but depleted in folate and vitamins B6...

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Detalhes bibliográficos
Main Authors: Hofmann, Marion A., Lalla, Evanthia, Lu, Yan, Gleason, Michelle Ryu, Wolf, Bonnie M., Tanji, Nozomu, Ferran, Luis J., Kohl, Brigitte, Rao, Vijay, Kisiel, Walter, Stern, David M., Schmidt, Ann Marie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC208940/
https://ncbi.nlm.nih.gov/pubmed/11254667
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