Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophages.
The phoP genetic locus is a two-component regulatory system (phoP-phoQ) that controls the expression of genes essential for Salmonella typhimurium virulence and survival within macrophages. Strains with a phoP constitutive mutation (phenotype PhoPC) showed up to 10-fold greater expression of phoP-ac...
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| Udgivet i: | J Bacteriol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1990
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2185222/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.5.2485-2490.1990 |
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