Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophages.

The phoP genetic locus is a two-component regulatory system (phoP-phoQ) that controls the expression of genes essential for Salmonella typhimurium virulence and survival within macrophages. Strains with a phoP constitutive mutation (phenotype PhoPC) showed up to 10-fold greater expression of phoP-ac...

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Pubblicato in:	J Bacteriol
Autori principali:	Miller, S I, Mekalanos, J J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2185222/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.5.2485-2490.1990
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