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The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences

The role of the hepatitis C virus (HCV) p7 protein in the virus life cycle is not known. Previous in vitro data indicated that this 63-aa polypeptide is located in the endoplasmic reticulum and has two transmembrane domains (TMDs) connected by a cytoplasmic loop; the amino- and carboxyl-terminal tai...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sakai, Akito, Claire, Marisa St., Faulk, Kristina, Govindarajan, Sugantha, Emerson, Suzanne U., Purcell, Robert H., Bukh, Jens
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14504405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1834545100
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